The Duke of York relinquishes his designation as Duke of York.
The royal is giving up his designations, including the Duke of York, he has stated in a individual message.
He has been under mounting scrutiny over his connections with disgraced financier the financier, with requests for the monarchy to take steps against him.
That now appears to have led to the royal deciding to voluntarily return his titles and to relinquish membership of the Garter Order.
In his message he said he continued to "strongly refute the allegations against me".
"In talks with the sovereign, and my close and broader family, we have decided the ongoing claims about me divert from the work of the monarch and the royal household," said a message from him.
"I have decided, as I always have, to put my duty to my relatives and nation first.
"I support my decision five years ago to withdraw from official duties.
"With the monarch's agreement, we feel I must now go a additional measure. I will therefore no longer use my title or the awards which have been granted to me. As I have said before, I strongly refute the allegations against me."
Prince Andrew has faced a range of issues, including a lawsuit he settled with Virginia Giuffre, questions about his finances and his association with an suspected Chinese spy.
He will remain a prince - but will stop to be the Duke of York, a honor received from his the late Queen, the former monarch.
The prince had already stopped to be a "active member" and had given up the use of his royal style and no longer appeared at public engagements. His position now will be even more reduced.
His ex-wife will be known as Ferguson and no longer Duchess of York, but their daughters will continue to have the designation of princesses.
Prince Andrew has been under severe attention over his links with convicted sex offender Epstein, more recently featuring inquiries about when he had truly severed communication.
In his media discussion, he had said that he had severed all links with Epstein after they had been seen together in the city in late 2010.
But correspondence sent in the following year later surfaced suggesting that the prince had in private continued in contact with him, such as exchanging a communication: "Keep in close touch and we'll play some more soon!"
There had been mounting annoyance in the monarchy at the controversies that remained to envelop the prince.
Soon a late publication by Virginia Giuffre will be released which is likely to cast more focus on the royal's connection with the plaintiff and Epstein.
